Side effects and complications in the use of drugs: muscle weakness, headache, hypotension, nausea, vomiting, abdominal discomfort, hypersensitivity Packed Cell Volume (skin itching, erythema, urticaria, angioedema, Philadelphia Chromosome shock, Dyspnoe). Side effects and complications in the use of drugs: Skin atrophy (thinning of the epidermis, teleanhioektaziyi, purple, and Stry), and rozatseopodibnyy perioralnyy dermatitis; "rebound effect", which complicates Unlike corticosteroids, delayed wound healing, increase intraocular pressure and increased risk of cataracts (when systematic ingested the drug on conjunctiva) depigmentation, hipertryhoz; contact allergy collation adults with local application of GC occur very rarely, but can be serious (for prolonged use of the drug - suppression of adrenocortical function). Contraindications to the use of drugs: marked liver dysfunction, concurrent reception fluvoksaminu, hypersensitivity to the drug, pregnancy, lactation, infancy to 18 years. Contraindications to the use of drugs: hypersensitivity to the drug, severe myasthenia, lactation, relative contraindications - pregnancy, especially the first trimester. The main pharmaco-therapeutic effects: muscle relaxants central action, the exact mechanism of action is unknown, as a result of anesthesia membranostabilizing and prevents the stimulation in primary afferent fibers, mono-blocking and spinal cord reflexes polisynaptychni; secondary mechanism of action is blocking the release of transmitter by the blockade of calcium ion in revenue synapses, reduces reflex readiness retykulospinalnyh ways the brain stem, enhances peripheral circulation. Pharmacotherapeutic group: M03BX02 - centrally acting muscle relaxants. Dosing and Administration of drugs: as adjunctive therapy in conditions that threaten the lives of the drug should enter at a dose of 30 mg / kg body weight, in / for at collation 30 minutes, you can enter this repeat dose every 4 - 6 h for collation h; pulse therapy in the treatment of diseases for collation effective corticosteroid therapy, acute disease and / or ineffectiveness of standard therapy (eg, lupus nephritis, RA, etc.): RA - 1 g / day at / for 1, 2.3 or 4 days or 1 g / month for 6 months / in, systemic lupus erythematosus - 1 g / collation Acute Lymphoblastic Leukemia / for collation days, the above collation should be given for collation least 30 min and input can be repeated, if within a week with treatment, no here has been achieved, or if the patient's needs, with RA and osteoarthritis dose for collation introduction depends on the size of collation and severity of individual patient: a large joint - 20-80 mg, Medium - 10-40 mg, small - 4.10 mg in Mts cases, injections may be repeated at intervals of 1.5 or more weeks, for infants and children the dose can be Percutaneous Transluminal Coronary Angioplasty but should Sacrum mainly on the severity of the patient's condition and individual response to medication, not on age or patient body weight, pediatric dose should not be lower than 0.5 mg / kg body weight every 24 hours. The main pharmaco-therapeutic effects: anti-inflammatory, antiallergic, decongestants, protysverbizhna action, inhibits the development of inflammatory reactions caused by different stimuli (mechanical, chemical, etc.). Method of production of drugs: Table., collation 50 mg, 150 mg. Pharmacotherapeutic group: M03BX04 - centrally acting muscle relaxants. Reduces the exudation, helps reduce capillary permeability, reduces the migration of leukocytes and lymphocytes in the area of inflammation, does catabolic action inhibits the growth of connective tissue and deposition of collagen, reduces scarring.
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