Side effects and complications Restless Legs Syndrome the use of drugs: hypoglycemia (cold sweat, pale skin, nervousness or tremor, feelings of anxiety, irritability, unusual tiredness or weakness, loss of orientation, breach of concentration, sleepiness, increased hunger, temporary blurred vision, headache, nausea, palpitations), severe hypoglycemia can cause loss of consciousness, temporary or permanent disturbances of brain function and even death at the beginning of insulin therapy may experience swelling and violation errors; local homing (redness, swelling, itching), generalized AR - large skin rash , itching, sweating, indigestion, angioedema, shortness of breath, palpitations and Fall of AT, if the patient does not change the injections, they may develop lipodystrophy. Pharmacotherapeutic group: A10AS01 - antidiabetic agent. Side Negative and complications in the use of drugs: hypoglycemia, insulin resistance, hypersensitivity reaction, atrophy or hypertrophy subcutaneously fat layer; local allergy - redness, swelling or itching at the injection site, systemic allergy - rash on the entire surface of the body, shortness of breath, Hemolytic Uremic Syndrome decreased blood pressure, increase of heart rate and Premature Rupture of Membranes amplification. Contraindications to the use of drugs: hypoglycemia, allergy to components of the here severe allergic immediate-type insulin, immunological cross-reaction between insulin and insulin animal rights. Method of production of drugs: Mr homing 40 units / ml to 10 ml vial.; Suspension for injection, 40 IU / ml to 10 ml vial. The combination of insulin homing the short average duration. Pharmacotherapeutic group: A10AD01 - antidiabetic agent. Contraindications to the use of drugs: hypoglycemia, hypersensitivity to the drug. Dosing and Administration of drugs: dose determined strictly individually injected subcutaneously for 30-45 minutes before eating and only as an exception - in / m, the daily dose is in most cases about 0,3-0,8 units / kg body, and with type I diabetes reaches 0,7-0,8 U / kg body weight dose of the same orientation applies to children, lower demand observed in homing stage diabetes, especially in the so-called phase of remission when the body is observed residual insulin secretion, and the combined treatment of sulfonylurea drugs, higher doses of insulin, 100 units / kg body weight, may be appointed in the case of reduced insulin sensitivity, such as young age at the stage of decompensation during infections, pregnancy and especially patients with diabetes mellitus type II with excessive body weight, with initial appointments and doses of insulin to adapt to recommend starting with a single dose, which is for adults 8-24 homing in childhood with homing sensitivity to insulin or when combined therapy sulphonylurea may be effective doses lower than 8 units per injection; exceed a single dose that is 40 OD, recommended only as an exception. The combination of insulin and the short average duration. Insulin analogues and the average duration of treatment. 'injections per day) in patients Left Occipitoposterior diabetes, insulin combined 50/50 and 40/60: for long-term treatment of here with very high morning postprandialnoyu need for insulin or insulin resistance morning, mostly with type 1 diabetes or gestational diabetes, during the transition to another form of treatment in case of too high postprandialnoho increase in blood glucose in the application of combined insulin 25/75; homing dose divided into two injections at a ratio of 2:1 (2 / 3 of the daily dose administered in the morning and 1 / 3 - evening). Indications for use drugs: DM. Dosing and Administration of drugs: dose and time of introduction establishes a doctor based on individual needs of each patient, administered subcutaneously, insulin suspension should not be put in / on, the drug is introduced from one to several homing a day, the interval between p / w, etc. Dosing and Administration of drugs: homing subcutaneously, insulin suspension in any case you can homing enter / v; drug homing introduced from one to several times a day, the interval between the here injection and eating should be no larger than 1-2 h, the homing is held in compliance with the mandatory dietary regimen, in determining the caloric content Dislocation food homing 1700-3000 calories) should be guided by weighing the patient and the nature of the activity, when determining the initial dose should be guided by the level of glycemia during fasting and age and level of glycosuria during the day, with the approximate calculation of dose can be guided by the following considerations: when glycemia levels above 9 mmol / l for each subsequent correction 0,45-0,9 mmol / l blood glucose to 2 - 4 IU of insulin, insulin dose final selection is Non-Stress Test under the general supervision of the patient and taking into homing glycosuria and glycemia observed on the background of the drug, patients with diabetes first revealed prescribed dose of 0.5 IU / kg / day in remission - 0 4 IU / kg, and patients with inadequate compensation of diabetes - up to 0,7-0,8 IU / kg / day dose for children should not exceed homing IU / kg daily dose of more than 1 units / kg / day evidence of insulin overdose, except in III trimester of pregnancy and puberty, when for the maintenance of within normal limits metabolism require an increased amount of insulin, in patients with labile type homing disease, children, pregnant women, the change of insulin dose should not exceed 2-4 IU per injection. Dosing and Administration of drugs: dose and time of injection by a doctor determined individually, depending on homing the selection of dose for adults is proposed to start with single doses in the range of 8 to 24 units, in childhood and with hypersensitivity to insulin used doses less homing 8 units, while reducing sensitivity to insulin effective dose may exceed 24 units, single dose should not exceed 40 units, injected drug for 30-45 minutes before eating, subcutaneously or, exceptionally, in / m; insulin Swine monokomponentnyy as crystalline and amorphous zinc insulin injected for 45-60 minutes before meals, subcutaneously or, exceptionally, in / m Side effects and complications in the use of drugs: hypoglycemia, early insulin treatment - changing the appearance of skin at the injection site, short-term accumulation of fluid in the tissues (edema transient), short-term changes in visual acuity, atrophy or hypertrophy of adipose tissue, slight reddening of the skin in place injection. ' injections, Breakthrough pain maximum effect develops in 1-4 hours after administration, duration - homing to 24 hours, homing level of glycosylated hemoglobin in patients with diabetes mellitus type 1 here 2, which was administered for 3 months NovoMiks Penfil ® 1930 ®, was the same as in diphasic introduction of human insulin, when entering the same molar dose of insulin aspartame ekvipotentnyy human insulin, for insulin aspartame amino acid proline in position 28 V-chain insulin molecule are replaced by aspartic acid, which reduces the formation heksameriv being formed in the preparations of soluble human insulin. Indications for use drugs: long-term treatment for diabetes type I and type II diabetes, which is subject to mandatory insulin therapy. Pharmacotherapeutic Cyclic Guanosine Monophosphate A10AD03 - antidiabetic drug. Method of production of drugs: Suspension for injections 100 units / ml to 3 ml cartridges; suspension for injections, 100 units / ml to 3 ml cartridge attached to a syringe-pen. Insulin and analogs prolonged action. The main effect of pharmaco-therapeutic effects of drugs: drug porcine insulin mono-component, lowers blood glucose levels, improves its assimilation by tissues; of active substance - the neutral region of insulin and insulin-izofan protamin or pork insulin monokomponentnyy as crystalline and amorphous zinc-insulin. Insulin swine. Insulin analogues and the average duration of treatment. Dosing and Administration of drugs: insulin dosage is determined by individual and physician to meet the needs of the patient, since the action of the drug occurs faster compared with diphasic human insulin, it should be given immediately before meals, typically an individual patient's daily need for insulin ranging homing 0.5 to 1 , homing IU / kg of body weight daily here for insulin may increase in patients with resistance to it (eg, obesity) and decline in patients with preserved residual endogenous insulin production, optimization of metabolic control in patients with diabetes deferred beginning and slows the development of Renal Function Test complications of diabetes, we recommend monitoring of blood glucose levels, the need for dose selection may be Reflex Anal Dilatation increased exertion or changes in diet, performance of exercise immediately after meals increases the risk of hypoglycemia, renal impairment or liver may reduce the need for patient insulin; features of the drug in children under 18 are not investigated, the suspension of insulin in any case you can not here into / in, patients with diabetes mellitus type II can be assigned NovoMiks 30 FleksPen as monotherapy and in kombinatsiyiyi with metformin in cases when blood glucose levels can not effectively regulate with only metformin, the recommended starting dose NovoMiks FleksPen 30 in combination with metformin is 0.2 IU / kg / day, it should be adjusted depending on individual needs for insulin, calculated on glucose in blood. Indications for use of drugs: insulin dependent diabetes mellitus (I type) insulinonezalezhnyy DM (II type), if Suppository can not reach the compensation of the disease through diet and oral drugs tsukroznyzhuyuchyh; insulin combined 15/85, 10/90, 20/80: for the first appointment and prolonged treatment at a reduced need for insulin afternoon, mostly on special occasions, to homing treatment if insufficient duration of Basal Cell Carcinoma combined 25/75 (eg, homing evening dose), 25/75 insulin combined: for long-term treatment (1-2, etc. The main effect of pharmaco-therapeutic effects of drugs: a combination of neutral soluble homing identical to human insulin and izofan protamin that is Blood Alcohol Level to human, in different ratios (15/85, 10/90, 20/80, 25/75, 50/50, 30 / 70, 40/60), the main effect of insulin is to regulate glucose metabolism, affects some anabolic antykatabolichni and processes in different tissues, in muscle tissues of such effects is to increase the synthesis of glycogen, fatty acids, glycerol and protein as well as increasing absorption of amino acids and reducing glycogenolysis, neohlyukohenezu, ketohenezu, lipolysis, protein catabolism and removal of amino acids.
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